Overview of Selected Chemical Compounds and Intermediates

Overview of Selected Chemical Compounds and Intermediates

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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is an impurity associated with bortezomib, a proteasome inhibitor Utilized in the treatment method of a number of myeloma. Its synthesis or examine is vital for ensuring the purity and protection on the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor in the synthesis of abiraterone acetate, a drug Employed in the treatment method of prostate most cancers by inhibiting androgen generation.
Imatinib Intermediate (CAS NO. 152460-10-one): A essential compound within the synthesis of imatinib, a drug that targets specific different types of most cancers, such as Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats many cancers including breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): These are intermediates from the synthesis of gemcitabine, an anti-cancer drug. Their examine is very important for optimizing the generation procedure and guaranteeing higher purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-five): Lapatinib is utilized to deal with breast most cancers, and these intermediates are involved in its creation.
Fulvestrant Intermediates: Fulvestrant can be an estrogen receptor antagonist used in the treatment method of breast most cancers. Various intermediates help in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-16-9): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug effective in treating cancers for example ovarian, breast, and lung most cancers.
three. Other Noteworthy Compounds
Irinotecan CAS NO. 848133-35-7 Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Employed in the treatment of colorectal cancer and tiny cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is associated with the synthesis of adamantane derivatives, which have different apps, which include antiviral Attributes.
Vildagliptin Intermediates: Employed in the creation of vildagliptin, an oral drug for type two diabetic issues that inhibits the enzyme DPP-four to control blood sugar concentrations.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-1): This compound is associated with the synthesis of varied gluconic acid derivatives, that happen to be Utilized in foods, pharmaceutical, and industrial programs.
Canagliflozin Intermediate 2: A precursor in the synthesis of canagliflozin, a medication utilized to handle kind 2 diabetic 5-dibenzoate(T6) issues by inhibiting sodium-glucose co-transporter two (SGLT2).